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EpoY

CAT: 0931-T201297-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0931-T201297-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
245660-13-3
Target
Others, Endogenous Metabolite
Related Pathways
Metabolism, Others
Bioactivity
EpoY (SD-142) is an irreversible inhibitor of the primary brain microtubule-associated tyrosine carboxypeptidase (TCP), a complex formed by vasohibin-1 (VASH1) and small vasohibin-binding protein (SVBP) . By inhibiting TCP with an IC50 value of approximately 500 nM, EpoY effectively reduces the levels of detyrosinated α-tubulin, which is crucial for microtubule dynamics and neuronal differentiation. This inhibition results in significant differentiation defects and is linked to potential issues related to cancer and cardiomyopathy.
Smiles
C(N[C@@H](CC1=CC=C(O)C=C1)C(O)=O)(=O)[C@@H]2[C@@H](C(OCC)=O)O2
Molecular Formula
C15H17NO7
Molecular Weight
323.3
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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CatalogName
GTR19239913-01EpoY

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