MED6-189

• Target :

  Parasite

• Related Pathways :

  Microbiology/Virology

• Bioactivity :

  MED6-189, an analog of kalihinol, disrupts the apicoplast functions and vesicular transport in the malignant malaria parasite (P. falciparum, IC50 < 50 nM) . The compound specifically targets the apicoplast, which is a non-photosynthetic plastid essential for isoprenoid synthesis, found in most apicomplexan parasites.

• Smiles :

  C(C)(C)[C@@H]1[C@@]2([C@@]([C@](C#N)(C)CC1)(CC[C@](C#N)(C)[C@@H]2O)[H])[H]

• Molecular Formula :

  C17H26N2O

• Molecular Weight :

  274.4

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2650073-66-6