MED6-189

• Target:

  Parasite

• Related Pathways:

  Microbiology/Virology

• Bioactivity:

  MED6-189, an analog of kalihinol, disrupts the apicoplast functions and vesicular transport in the malignant malaria parasite (P. falciparum, IC50 < 50 nM) . The compound specifically targets the apicoplast, which is a non-photosynthetic plastid essential for isoprenoid synthesis, found in most apicomplexan parasites.

• Smiles:

  C(C)(C)[C@@H]1[C@@]2([C@@]([C@](C#N)(C)CC1)(CC[C@](C#N)(C)[C@@H]2O)[H])[H]

• Molecular Formula:

  C17H26N2O

• Molecular Weight:

  274.4

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2650073-66-6