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Alkyne-P60

CAT: 0931-T201285-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T201285-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Ligands for Target Protein for PROTAC
Related Pathways
PROTAC
Bioactivity
Alkyne-P60 is an effective 15-peptide inhibitor of Foxp3. It binds with Foxp3, inhibiting its nuclear translocation and attenuating the suppression of NFKB and NFAT functions mediated by Foxp3. Furthermore, Alkyne-P60 serves as a ligand for PROTAC target proteins.
Smiles
NC(NCCC[C@@H](C(N[C@@H](CC(O)=O)C(N[C@@H](CC1=CC=CC=C1)C(N[C@H](C(N[C@H](C(N[C@@H](CC2=CC=CC=C2)C(N[C@H](C(N[C@H](C(N[C@@H](CCSC)C(N[C@@H](CC3=CNC4=C3C=CC=C4)C(N5CCC[C@H]5C(N[C@@H](CC6=CC=CC=C6)C(N[C@@H](CC7=CC=CC=C7)C(N[C@@H](C)C(N[C@@H](CCSC)C(N)=O)=O)=O)=O)=O)=O)=O)=O)CCCCN)=O)CCCNC(N)=N)=O)=O)CO)=O)CCC(N)=O)=O)=O)=O)NC(CCCC#C)=O)=N
Molecular Formula
C101H139N25O20S2
Molecular Weight
2087.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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