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Claturafenib

CAT: 0931-T201081-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0931-T201081-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2754408-94-9
Target
PERK, Raf
Related Pathways
Apoptosis, MAPK
Purity
≥99.99%
Bioactivity
Claturafenib (PF-07799933) is a brain-permeable, selective, all-mutant BRAF inhibitor with broad inhibitory effects on pERK levels in HT29 cells.Claturafenib has shown antitumor activity in preclinical studies in both BRAF V600- and non-V600-mutant cancers and can be used in combination with MEK inhibitors.
Smiles
O=C1C2=C(N=CN1C)C=CC(NC=3C(F)=CC=C(NS(=O)(=O)N4CC(F)C4)C3Cl)=C2Cl
Molecular Formula
C18H15Cl2F2N5O3S
Molecular Weight
490.31
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
HY-159795-01Claturafenib
C03279-1gClaturafenib (PF-07799933)

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