Products for Research Use Only
RegisterLogin

Gridegalutamide

CAT: 0931-T200967-02Size: 50 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T200967-02Size:50 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
2446929-86-6
Target
Androgen Receptor
Related Pathways
Endocrinology/Hormones
Bioactivity
Gridegalutamide exhibits anti-androgen and anti-tumor activities.
Smiles
S=C1N(C(=O)C(C)(C)N1C2=CC(CC)=C(OCCN3C[C@@H](C)N(CC(NC4=CC(N[C@H]5C(=O)NC(=O)CC5)=CC=C4)=O)CC3)C=C2)C6=CC(C(F)(F)F)=C(C#N)C=C6
Molecular Formula
C41H45F3N8O5S
Molecular Weight
818.91
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

Gridegalutamide

Gridegalutamide is a small molecule drug. The usage of the INN stem '-lutamide' in the name indicates that Gridegalutamide is a non-steroid antiandrogen. Gridegalutamide is under investigation in clinical trial NCT04428788 (Study to Evaluate the Safety and Tolerability of CC-94676 in Participants With Metastatic Castration-Resistant Prostate Cancer). Gridegalutamide has a monoisotopic molecular weight of 818.32 Da.

CAS Number2446929-86-6
PubChem CID153513643
IUPAC Name2-[(2R)-4-[2-[4-[3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-sulfanylideneimidazolidin-1-yl]-2-ethylphenoxy]ethyl]-2-methylpiperazin-1-yl]-N-[3-[[(3R)-2,6-dioxopiperidin-3-yl]amino]phenyl]acetamide
Molecular FormulaC41H45F3N8O5S
Molecular Weight818.9
XLogP5.4
Topological Polar Surface Area182
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count13
Rotatable Bond Count12
Heavy Atom Count58
Formal Charge0
Complexity1590
SMILES
CCC1=C(C=CC(=C1)N2C(=S)N(C(=O)C2(C)C)C3=CC(=C(C=C3)C#N)C(F)(F)F)OCCN4CCN([C@@H](C4)C)CC(=O)NC5=CC=CC(=C5)N[C@@H]6CCC(=O)NC6=O
InChI
InChI=1S/C41H45F3N8O5S/c1-5-26-19-31(52-39(58)51(38(56)40(52,3)4)30-10-9-27(22-45)32(21-30)41(42,43)44)11-13-34(26)57-18-17-49-15-16-50(25(2)23-49)24-36(54)47-29-8-6-7-28(20-29)46-33-12-14-35(53)48-37(33)55/h6-11,13,19-21,25,33,46H,5,12,14-18,23-24H2,1-4H3,(H,47,54)(H,48,53,55)/t25-,33-/m1/s1
InChIKey
YUVGVJYLOFTILT-INJOXJOKSA-N
Chemical Structure
2D Structure
2D structure of Gridegalutamide
CAS: 2446929-86-6
CID: 153513643
Formula: C41H45F3N8O5S
MW: 818.9
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight818.9
XLogP35.4
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count13
Rotatable Bond Count12
Exact Mass818.31857223
Monoisotopic Mass818.31857223
Topological Polar Surface Area182 Ų
Heavy Atom Count58
Formal Charge0
Complexity1590
Isotope Atom Count0
Defined Atom Stereocenter Count2
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
HY-159844-01Gridegalutamide
A23930-5Gridegalutamide (BMS-986365) 5mg
A23930-10Gridegalutamide (BMS-986365) 10mg
A23930-50Gridegalutamide (BMS-986365) 50mg
A23930-1Gridegalutamide (BMS-986365) 1mg

Popular Products