C-Kit-IN-8

CAT: 0931-MF-0142708-01Size: 100 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0142708-01Size:100 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2941024-89-9
Target
C-Kit
Related Pathways
Tyrosine Kinase/Adaptors
Bioactivity
C-Kit-IN-8 (Compound 53) acts as an inhibitor of c-Kit kinase, hampering uKIT kinase activity with an IC50 greater than 1 ?M. Additionally, it inhibits the proliferation of both wild-type and mutant GIST430 and BaF3 cancer cells, exhibiting an IC50 greater than 0.1 ?M.
Smiles
O=C(NC1=CC=C(C=C1)NC=2N=CN=C3C=C(OCCOC)C=C(F)C32)CCN4C(=O)CCC4
Molecular Formula
C24H26FN5O4
Molecular Weight
467.49
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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