C-Kit-IN-8

• Target :

  C-Kit

• Related Pathways :

  Tyrosine Kinase/Adaptors

• Bioactivity :

  C-Kit-IN-8 (Compound 53) acts as an inhibitor of c-Kit kinase, hampering uKIT kinase activity with an IC50 greater than 1 ?M. Additionally, it inhibits the proliferation of both wild-type and mutant GIST430 and BaF3 cancer cells, exhibiting an IC50 greater than 0.1 ?M.

• Smiles :

  O=C(NC1=CC=C(C=C1)NC=2N=CN=C3C=C(OCCOC)C=C(F)C32)CCN4C(=O)CCC4

• Molecular Formula :

  C24H26FN5O4

• Molecular Weight :

  467.49

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2941024-89-9