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SW063058

CAT: 0931-T200877-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0931-T200877-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
533876-30-1
Target
Autophagy, Others
Related Pathways
Autophagy, Others
Bioactivity
SW063058 is an autophagy inducer that specifically disrupts the interaction between Beclin 1 and Bcl-2 without affecting the interactions of Bcl-2 with pro-apoptotic members (such as Bax and BIM) . By inhibiting the negative regulation of Beclin 1 (key to autophagy initiation) by Bcl-2, SW063058 enhances autophagic activity without inducing cytotoxicity, apoptosis, or other forms of cell death in vitro.
Smiles
O=C1NC2=CC=C(Br)C=C2C(C3=CC=C(F)C=C3)N(C(=O)C=4C=CC=CC4I)C1
Molecular Formula
C22H15BrFIN2O2
Molecular Weight
565.17
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
HY-122047SW063058

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