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DBCO-PEG3-VC-Exatecan

CAT: 0931-T200875-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T200875-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2754384-70-6
Target
Drug-Linker Conjugates for ADC, Topoisomerase
Related Pathways
Antibody-drug Conjugate/ADC Related, DNA Damage/DNA Repair
Bioactivity
DBCO-PEG3-VC-Exatecan (compound 25) is a Drug-Linker Conjugate for ADC (ADC Drug-Linker Conjugate), consisting of the ADC linker (DBCO-PEG3-VC) coupled with the DNA topoisomerase I (topoisomeraseI) inhibitor Exatecan. This conjugate is utilized in the development of antibody-drug conjugates for targeted cancer therapy.
Smiles
N(C(OCC1=CC=C(NC([C@@H](NC([C@@H](NC(CCOCCOCCOCCNC(CCC(=O)N2C=3C(C#CC=4C(C2)=CC=CC4)=CC=CC3)=O)=O)[C@@H](C)C)=O)CCCNC(N)=O)=O)C=C1)=O)[C@@H]5C6=C7C(C=8N(C7)C(=O)C9=C(C8)[C@](CC)(O)C(=O)OC9)=NC=%10C6=C(CC5)C(C)=C(F)C%10
Molecular Formula
C71H79FN10O15
Molecular Weight
1331.44
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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HY-164792-01DBCO-PEG3-VC-Exatecan
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