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FKB04

CAT: 0931-T200635-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T200635-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Target
Others, Telomerase
Related Pathways
Others, DNA Damage/DNA Repair
Bioactivity
FKB04 is a telomeric repeat binding factor 2 (TRF2) inhibitor that exerts its antitumor activity by disrupting the telomere maintenance mechanisms in hepatocellular carcinoma cells. This leads to T-loop defects, inducing telomere shortening and cellular senescence. Additionally, FKB04 inhibits tumor growth in a human liver cancer xenograft mouse model (by implanting Huh-7 cells in BALB/c mice) . This compound is utilized in research focused on liver cancer.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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