Products for Research Use Only

L18I

CAT: 0931-T200405-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T200405-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
BTK, PROTACs
Related Pathways
Tyrosine Kinase/Adaptors, PROTAC, Angiogenesis
Bioactivity
L18I is a PROTAC (Proteolysis Targeting Chimera) that targets Btk to mitigate inflammation in autoimmune diseases. The components of L18I include the PROTAC target protein ligand IBT6A, the PROTAC linker Propargyl-PEG3-alcohol, and the E3 ubiquitin ligase ligand Lenalidomide-Br. Notably, the active control for the target protein ligand is IBT6A-CO-ethyne, while the conjugate of the E3 ubiquitin ligase ligand with the linker is Lenalidomide-C3-PEG3-N3.
Molecular Formula
C47H51N11O8
Molecular Weight
897.98
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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