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ZX782

CAT: 0931-T200295-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T200295-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
PROTACs, Ferroptosis, Glutathione Peroxidase
Related Pathways
Metabolism, PROTAC, Apoptosis
Bioactivity
ZX782 acts as a GPX4 protein degrader and an inducer of ferroptosis (Ferroptosis), targeting GPX4 for destruction via both the ubiquitin-proteasome system and the autophagy-lysosome pathway. Following the degradation of GPX4 induced by ZX782, there is a significant increase in the accumulation of lipid reactive oxygen species (ROS) in HT1080 cells.
Molecular Formula
C39H48ClN5O8
Molecular Weight
750.28
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
HY-161972ZX782

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