PF-07899895

• Target:

  SIK

• Related Pathways:

  PI3K/Akt/mTOR signaling

• Bioactivity:

  PF-07899895 (compound 34) is a potent SIK (salt-induced kinase) inhibitor with IC50 values of 1.2/0.9/1.8 nM for SIK1/SIK2/SIK3.

• Smiles:

  N#CC1=CC=CC2=NC=C (C=3C=C (OCC4 (N) CCCCC4) C (C#N) =C (SC) C3) N12

• Molecular Formula:

  C23H23N5OS

• Molecular Weight:

  417.53

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  3033846-10-2