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MC3629

CAT: 0931-T200181-02Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0931-T200181-02Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1375163-30-6
Target
Apoptosis, Histone Methyltransferase
Related Pathways
Chromatin/Epigenetic, Apoptosis
Bioactivity
MC3629, an inhibitor of the histone methyltransferase (EZH2), exhibits antitumor activity. This compound effectively inhibits the proliferation and self-renewal of SHH MB cancer cells while inducing cell apoptosis (apoptosis) . MC3629 is also useful in research on tumor aggressiveness and resistance.
Smiles
O=C(NCC=1C(=O)NC(=CC1C)C)C=2C=NN(C=3C=CC=CC3)C2C
Molecular Formula
C19H20N4O2
Molecular Weight
336.39
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-5-methyl-1-phenyl-1H-pyrazole-4-carboxamide
CAS Number1375163-30-6
PubChem CID34244817
IUPAC NameN-[(4,6-dimethyl-2-oxo-1H-pyridin-3-yl)methyl]-5-methyl-1-phenylpyrazole-4-carboxamide
Molecular FormulaC19H20N4O2
Molecular Weight336.4
XLogP2.2
Topological Polar Surface Area76
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count3
Rotatable Bond Count4
Heavy Atom Count25
Formal Charge0
Complexity605
SMILES
CC1=CC(=C(C(=O)N1)CNC(=O)C2=C(N(N=C2)C3=CC=CC=C3)C)C
InChI
InChI=1S/C19H20N4O2/c1-12-9-13(2)22-19(25)16(12)10-20-18(24)17-11-21-23(14(17)3)15-7-5-4-6-8-15/h4-9,11H,10H2,1-3H3,(H,20,24)(H,22,25)
InChIKey
LLWAEAQGDHLXKV-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-5-methyl-1-phenyl-1H-pyrazole-4-carboxamide
CAS: 1375163-30-6
CID: 34244817
Formula: C19H20N4O2
MW: 336.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight336.4
XLogP32.2
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count3
Rotatable Bond Count4
Exact Mass336.15862589
Monoisotopic Mass336.15862589
Topological Polar Surface Area76 Ų
Heavy Atom Count25
Formal Charge0
Complexity605
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
HY-164500MC3629

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