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CYP51-IN-20

CAT: 0931-T200116-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T200116-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Antifungal, Cytochromes P450
Related Pathways
Metabolism, Microbiology/Virology
Bioactivity
CYP51-IN-20 (compound 5b), an antifungal agent, effectively inhibits CYP51 and exhibits significant activity against Candida albicans ATCC 10231. It suppresses the ERG11 (Cyp51) gene expression and markedly curtails the morphological transformation from yeast to hyphae. Furthermore, when combined with Voriconazole, CYP51-IN-20 synergistically occupies the entire CYP51 binding site, enhancing its inhibitory impact in the Glechoma moth model.
Molecular Formula
C24H30N6O4
Molecular Weight
466.53
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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