WK88-1

CAT: 0931-T200115-01Size: 100 mgDry Ice: NoHazardous: No

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CAT#:0931-T200115-01Size:100 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

958888-32-9

Target

Apoptosis, HSP

Related Pathways

Apoptosis, Metabolism, Cytoskeletal Signaling

Bioactivity

WK88-1, an inhibitor of Hsp90, effectively induces the degradation of various oncogenic signaling molecules, including EGFR, ErbB2, and ErbB3, in the gefitinib-resistant H1975 cell line. This leads to subsequent growth arrest and apoptosis.

Smiles

CO[C@H]1CC\C=C(C)/C(=O)NC2=CC(C[C@@H](C)C[C@H](OC)[C@H](O)[C@@H](C)\C=C(C)\[C@H]1OC(N)=O)=CC=C2

Molecular Formula

C28H42N2O6

Molecular Weight

502.64

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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Catalog	Name
GTR19239250-01	WK88-1
OF59775-01	1,1,1,1,1-Kestoheptaose
N2864-5.1	1,1,1,1-Kestohexaose
112040	1,1,1,1-Kestohexose
410417-01	1,1,1-Trichloromethanesulfonic Acid 1,1'-Anhydride
IFA69273-01	1-Iodobicyclo[1.1.1]pentane
OR312388	1-Phenylbicyclo[1.1.1]pentane
GTR19217879-01	AMPK-α1β1γ1 activator 1
OR300179	1-Isothiocyanatobicyclo[1.1.1]pentane

WK88-1

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