G-631

CAT: 0931-MF-0142419-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0142419-01Size:25 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1507370-78-6
Target
PARP
Related Pathways
DNA Damage/DNA Repair|||Chromatin/Epigenetic
Bioactivity
G-631 acts as a selective tankyrase inhibitor, effectively hindering tankyrase auto-PARsylation (poly ADP ribosylation) at an IC 50 of 7 nM and suppressing the Wnt signaling pathway. This compound also demonstrates favorable pharmacokinetic properties in mice.
Smiles
O=C1N=C(NC2=C1C=NN2C)N3CCN(C4=C(F)C=C(OCCOC)C=C4F)CC3
Molecular Formula
C19H22F2N6O3
Molecular Weight
420.41
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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