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Recombinant human RAB5A protein

CAT: 0112-RAB0701-500Size: 500 µgDry Ice: NoHazardous: No
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CAT#:0112-RAB0701-500Size:500 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Rab5a is a member of RAS oncogene family. The small GTPase, Rab5a is a crucial regulatory component of the endocytic pathway. Activation of Rab5a is mediated by GDP-GTP exchange factors (GEFs) that generate the Rab5-GTP complex. Recombinant human Rab5a was expressed in E. coli and purified by using conventional chromatography techniques.
Product Name Alternative
RAB5A member RAS oncogene family, Ras-related protein Rab-5A, RAS-associated protein RAB5A, RAB5
Expression System
E.coli
Antigen Species
Human
Tag
Non-Tagged
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 95% by SDS-PAGE
Molecular Weight
23 kDa (215aa) confirmed by MALDI-TOF
Additionnal Information
Rab5a, RAB0701-10 µg, RAB0701-20 µg, RAB0701-50 µg, RAB0701-100 µg, RAB0701-250 µg, RAB0701-500 µg, RAB0701-1 mg, RAB0701-10, RAB0701-20, RAB0701-50, RAB0701-100, RAB0701-250, RAB0701-500, RAB0701-1
References & Citations
Tan BK, et al. (2007) J Clin Endocrinol Metab. 92 (7) :2590-7 ; ; Yao-Borengasser A, et al. (2007) ) J Clin Endocrinol Metab. 92 (7) :2430-2. ;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM MES buffer (pH 6.0) containing 10% glycerol, 0.1mM PMSF
Scientific Category
Cancer
NCBI Accession Number
NP_004153
Uniprot Accession Number
P20339
Species
Human
AA Sequence
MASRGATRPN GPNTGNKICQ FKLVLLGESA VGKSSLVLRF VKGQFHEFQE STIGAAFLTQ TVCLDDTTVK FEIWDTAGQE RYHSLAPMYY RGAQAAIVVY DITNEESFAR AKNWVKELQR QASPNIVIAL SGNKADLANK RAVDFQEAQS YADDNSLLFM ETSAKTSMNV NEIFMAIAKK LPKNEPQNPG ANSARGRGVD LTEPTQPTRN QCCSN