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Recombinant human IRF2 protein

CAT: 0112-IRF0703-500Size: 500 µgDry Ice: NoHazardous: No
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CAT#:0112-IRF0703-500Size:500 µg
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Description
Interferon regulatory factor (IRF) 2 is a member of the interferon regulatory transcription factor family. IRF-2 is generally regarded as an oncoprotein. Structure of IRF1 and IRF2 are similar. However, its functions are different. IRF2 competitively inhibits the IRF1-mediated transcriptional activation of interferons alpha and beta, and presumably other genes that employ IRF1 for transcription activation. Recombinant human IRF2 was expressed in E. coli and purified by using conventional chromatography techniques.
Product Name Alternative
Interferon regulatory factor-2, Interferon regulatory factor 2, DKFZp686F0244, IRF2, IRF2, 1-113 aa His-tagged, IRF-2, Interferon regulatory factor-2 IRF 2.
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 95% by SDS-PAGE
Molecular Weight
15 kDa (133aa) confirmed by MALDI-TOF
Additionnal Information
IRF2, Interferon regulatory factor-2, Interferon regulatory factor 2, DKFZp686F0244, IRF2, IRF2, 1-113 aa His-tagged, IRF-2, Interferon regulatory factor-2 IRF 2., IRF0703-10 µg, IRF0703-20 µg, IRF0703-50 µg, IRF0703-100 µg, IRF0703-250 µg, IRF0703-500 µg, IRF0703-1 mg, IRF0703-10, IRF0703-20, IRF0703-50, IRF0703-100, IRF0703-250, IRF0703-500, IRF0703-1
References & Citations
Harada, H., et al. (1989) Cell. 58 (4) :729-739 ; ; Matsuyama T., et al. (1993) Cell 75 (1) :83-97 ;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol
Scientific Category
Hormones & Cytokines
NCBI Accession Number
NP_002190
Uniprot Accession Number
P14316
Species
Human
AA Sequence
MPVERMRMRP WLEEQINSNT IPGLKWLNKE KKIFQIPWMH AARHGWDVEK DAPLFRNWAI HTGKHQPGVD KPDPKTWKAN FRCAMNSLPD IEEVKDKSIK KGNNAFRVYR MLP