Recombinant mouse CD200 protein

CAT: 0112-ATGP3964-020Size: 20 µgDry Ice: NoHazardous: No
CAT#:0112-ATGP3964-020Size:20 µg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CD200, also known as OX-2 membrane glycoprotein isoform 1, is one of the immunoglobulin superfamily. It plays an important role in anti-tumor immunity through interaction with its receptor, and overexpression of this protein effects on malignancies as well as on cancer stem cells. In T cells, this protein functions as a co-stimulatory effect that is independent of the CD28 pathway. It also plays an important role on myeloid cell regulation that is suggested by restricted expression of its receptor. Studies of this protein in mouse and rat suggest that this gene may regulate myeloid cell activity and delivers an inhibitory signal for the macrophage lineage in diverse tissues. Recombinant mouse CD200, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Specifications
Mouse CD200 is coated at 1 µg/mL (100 ul/well) can bind CD200 R1 (CAT# ATGP3457) in a Functional ELISA assay.
Product Name Alternative
Cd200, Mox2, OX2, OX-2 membrane glycoprotein isoform 1, MRC OX-2 antigen
Expression System
Baculovirus
Antigen Species
Mouse
Tag
His-Tag
Applications
SDS-PAGE, Bioactivity
Concentration
0.25 mg/mL (determined by absorbance at 280 nm)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 95% by SDS-PAGE
Bioactivity
Measured by its binding ability in a functional ELISA with Mouse CD200 R1 (CAT# ATGP3457)
Molecular Weight
23.5 kDa (210aa)
Additionnal Information
, ATGP3964-10 µg, ATGP3964-20 µg, ATGP3964-50 µg, ATGP3964-100 µg, ATGP3964-250 µg, ATGP3964-500 µg, ATGP3964-1 mg, ATGP3964-10, ATGP3964-20, ATGP3964-50, ATGP3964-100, ATGP3964-250, ATGP3964-500, ATGP3964-1
References & Citations
Poongodi R., et al. (2018) Indian J Pathol Microbiol. 61:50-57. ; ; Kuwabara J., et al. (2018) Biochem Biophys Res Commun. 496:542-548.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Immunology
NCBI Accession Number
NP_034948
Uniprot Accession Number
O54901
Species
Mouse
N Terminal Sequence
Gln31