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Recombinant human UbcH5b/UBE2D2 protein

CAT: 0112-ATGP3690-100Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP3690-100Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
UBE2D2, also known as Ubiquitin-conjugating enzyme E2 D2, is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. UBE2D2 catalyzes ubiquitination of IkB-alpha in a phosphorylation and SCFB-TRCP dependent manner. Recombinant human UBE2D2 protein was expressed in E. coli and purified by using conventional chromatography techniques.
Product Name Alternative
Ubiquitin-conjugating enzyme E2 D2, Ubiquitin carrier protein D2, Ubiquitin-conjugating enzyme E2 (17) KB 2, Ubiquitin-conjugating enzyme E2-17 kDa 2, Ubiquitin-protein ligase D2, p53-regulated ubiquitin-conjugating enzyme 1, PUBC1, UBC4, UBC5B, UBCH4, UBCH5B
Expression System
E.coli
Antigen Species
Human
Tag
Non-Tagged
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by absorbance at 280 nm)
Purity
> 95% by SDS-PAGE
Molecular Weight
16.7 kDa (147aa) Confirmed by MALDI-TOF
Additionnal Information
UbcH5b, UBE2D2, Ubiquitin-conjugating enzyme E2 D2 isoform1, E2 (17) KB2, PUBC1, UBC4, UBC4/5, UBCH4, UBCH5B, ATGP3690-10 µg, ATGP3690-20 µg, ATGP3690-50 µg, ATGP3690-100 µg, ATGP3690-250 µg, ATGP3690-500 µg, ATGP3690-1 mg, ATGP3690-10, ATGP3690-20, ATGP3690-50, ATGP3690-100, ATGP3690-250, ATGP3690-500, ATGP3690-1
References & Citations
Ciechanover A., et al. (1994) FASEB J. 8 (2) :182-91.; ; Orian A., et al. (1995) J Biol Chem. 270 (37) :21707-14.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM MES buffer (pH 6.0) containing 50 mM NaCl, 1mM DTT
Scientific Category
Ubiquitination
NCBI Accession Number
NP_003330
Uniprot Accession Number
P62837
Species
Human
AA Sequence
MALKRIHKEL NDLARDPPAQ CSAGPVGDDM FHWQATIMGP NDSPYQGGVF FLTIHFPTDY PFKPPKVAFT TRIYHPNINS NGSICLDILR SQWSPALTIS KVLLSICSLL CDPNPDDPLV PEIARIYKTD REKYNRIARE WTQKYAM

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