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Recombinant human IL-7 protein

CAT: 0112-ATGP3442-100Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP3442-100Size:100 µg
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Description
IL7, as known as interleukin-7 isoform 1, is a cytokine of the hemopoietin family that plays important roles in lymphocyte differentiation, proliferation, and survival. This protein is a hematopoietic growth factor secreted by stromal cells in the bone marrow and thymus. It is also produced by keratinocytes, dendritic cells, hepatocytes, neurons, and epithelial cells but is not produced by normal lymphocytes. Recombinant human IL7, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Product Name Alternative
Interleukin-7 isoform 1, IL7, IL-7, Il7, Interleukin-7
Expression System
Baculovirus
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by absorbance at 280 nm)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 90% by SDS-PAGE
Molecular Weight
18.4 kDa (161aa)
Additionnal Information
Interleukin-7 isoform 1, IL 7, IL7, IL-7, Interleukin-7, Interleukin7, Interleukin 7, ATGP3442-10 µg, ATGP3442-20 µg, ATGP3442-50 µg, ATGP3442-100 µg, ATGP3442-250 µg, ATGP3442-500 µg, ATGP3442-1 mg, ATGP3442-010, ATGP3442-020, ATGP3442-050, ATGP3442-100, ATGP3442-250, ATGP3442-500, ATGP3442-01M
References & Citations
Iolyeva M., et al. (2013) Blood 122:2271-2281.; ; Younas M., et al. (2013) J. Immunol. 191:3161-3168.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Hormones & Cytokines
NCBI Accession Number
NP_000871.1
Uniprot Accession Number
P13232
Species
Human
N Terminal Sequence
Ala
AA Sequence
DCDIEGK DGKQYESVLM VSIDQLLDSM KEIGSNCLNN EFNFFKRHIC DANKEGMFLF RAARKLRQFL KMNSTGDFDL HLLKVSEGTT ILLNCTGQVK GRKPAALGEA QPTKSLEENK SLKEQKKLND LCFLKRLLQE IKTCWNKILM GTKEH

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