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Recombinant human TPST2 protein

CAT: 0112-ATGP3332-250Size: 250 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP3332-250Size:250 µg
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Description
TPST2, also known as protein-tyrosine sulfotransferase 2, is the enzyme that catalyzes the sulfation reaction of protein tyrosines, a post-translational modification of proteins. This protein is a type II integral membrane protein found in the Golgi body. Compared to TPST1, TPST2 has similar tissue distribution and overlapping substrate specificity. In contrast to TPST1-/- males with normal fertility in mice, TPST2-/- males are infertile due to severe defects in sperm motility. Recombinant human TPST2, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Product Name Alternative
Protein-tyrosine sulfotransferase 2, TANGO13B
Expression System
Baculovirus
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.25 mg/mL (determined by absorbance at 280 nm)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 95% by SDS-PAGE
Molecular Weight
40.4 kDa (361aa)
Additionnal Information
TPST2, Protein-tyrosine sulfotransferase 2, TANGO13B, ATGP3332-10 µg, ATGP3332-20 µg, ATGP3332-50 µg, ATGP3332-100 µg, ATGP3332-250 µg, ATGP3332-500 µg, ATGP3332-1 mg, ATGP3332-10, ATGP3332-20, ATGP3332-50, ATGP3332-100, ATGP3332-250, ATGP3332-500, ATGP3332-1
References & Citations
Danan LM., et al. (2008) . J Am Soc Mass Spectrom. 19 (10) :1459-1466.; ; Kehoe J.W. and Bertozzi C.R. (2000) Chemistry & Biology. 7:57-61.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Cardiovascular
NCBI Accession Number
NP_001008566.1
Uniprot Accession Number
O60704
Species
Human
N Terminal Sequence
Ala
AA Sequence
QQVLECR AVLAGLRSPR GAMRPEQEEL VMVGTNHVEY RYGKAMPLIF VGGVPRSGTT LMRAMLDAHP EVRCGEETRI IPRVLAMRQA WSKSGREKLR LDEAGVTDEV LDAAMQAFIL EVIAKHGEPA RVLCNKDPFT LKSSVYLSRL FPNSKFLLMV RDGRASVHSM ITRKVTIAGF DLSSYRDCLT KWNKAIEVMY AQCMEVGKEK CLPVYYEQLV LHPRRSLKLI LDFLGIAWSD AVLHHEDLIG KPGGVSLSKI ERSTDQVIKP VNLEALSKWT GHIPGDVVRD MAQIAPMLAQ LGYDPYANPP NYGNPDPFVI NNTQRVLKGD YKTPANLKGY FQVNQNSTSS HLGSS

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