Recombinant mouse CD14 protein

• Description:

  Cd14, also known as monocyte differentiation antigen CD14, is a component of the innate immune system. This protein was found expressed in macrophages, neutrophil granulocyte and dendritic cells. It exists in two forms, one anchored to the membrane by a glycosylphosphatidylinositol tail (mCD14), the other a soluble form (sCD14) . The major function is serve as a co-receptor (along with TLR4 and MD-2) for the bacterial lipopolysaccharide (LPS) and other pathogen-associated molecular patterns. Recombinant Mouse Cd14, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

• Product Name Alternative:

  Monocyte differentiation antigen CD14, CD14 molecule, Myeloid cell-specific leucine-rich glycoprotein

• Expression System:

  Baculovirus

• Antigen Species:

  Mouse

• Tag:

  His-Tag

• Applications:

  SDS-PAGE

• Concentration:

  0.5 mg/mL (determined by absorbance at 280 nm)

• Endotoxin:

  < 1 EU per 1ug of protein (determined by LAL method)

• Purity:

  > 90% by SDS-PAGE

• Molecular Weight:

  38.3 kDa (357aa)

• Additionnal Information:

  CD14, ATGP3175-10 µg, ATGP3175-20 µg, ATGP3175-50 µg, ATGP3175-100 µg, ATGP3175-250 µg, ATGP3175-500 µg, ATGP3175-1 mg, ATGP3175-10, ATGP3175-20, ATGP3175-50, ATGP3175-100, ATGP3175-250, ATGP3175-500, ATGP3175-1

• References & Citations:

  Ferrero E., et al. (1990) J Immunol. 45 (1) :331-336.; ; SD Wright., et al. (1990) Science. 249:1431-1433.

• Storage Conditions:

  Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

• Formulation:

  Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

• Scientific Category:

  Immunology

• NCBI Accession Number:

  NP_033971

• Uniprot Accession Number:

  P10810

• Species:

  Mouse