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Recombinant human PGM1 protein

CAT: 0112-ATGP3158-500Size: 500 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP3158-500Size:500 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PGM1 also known as Phosphoglucomutase-1 isoform 1. PGM1 belongs to the phosphohexose mutase family. There are several PGM isozymes, which are catalyze the transfer of phosphate between the 1 and 6 positions of glucose. In most cell types, PGM1 isozymes predominate, representing about 90% of total PGM activity. Defects in PGM1 are the cause of glycogen storage disease type 14. Recombinant human PGM1, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques
Product Name Alternative
Phosphoglucomutase-1 isoform 1, CDG1T, GSD14
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by absorbance at 280 nm)
Purity
> 95% by SDS-PAGE
Molecular Weight
63.8 kDa (585aa)
Additionnal Information
PGM1, Phosphoglucomutase-1 isoform 1, CDG1T, GSD14, ATGP3158-10 µg, ATGP3158-20 µg, ATGP3158-50 µg, ATGP3158-100 µg, ATGP3158-250 µg, ATGP3158-500 µg, ATGP3158-1 mg, ATGP3158-10, ATGP3158-20, ATGP3158-50, ATGP3158-100, ATGP3158-250, ATGP3158-500, ATGP3158-1
References & Citations
Gururaj A., et al (2004) . Oncogene. 23 (49) :8118-27.; ; Stojkovic T., et al (2009) . N. Engl. J. Med. 361 (4) :425-7.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Metabolism
NCBI Accession Number
NP_002624
Uniprot Accession Number
P36871
Species
Human
AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSMVKIVTV KTQAYQDQKP GTSGLRKRVK VFQSSANYAE NFIQSIISTV EPAQRQEATL VVGGDGRFYM KEAIQLIARI AAANGIGRLV IGQNGILSTP AVSCIIRKIK AIGGIILTAS HNPGGPNGDF GIKFNISNGG PAPEAITDKI FQISKTIEEY AVCPDLKVDL GVLGKQQFDL ENKFKPFTVE IVDSVEAYAT MLRSIFDFSA LKELLSGPNR LKIRIDAMHG VVGPYVKKIL CEELGAPANS AVNCVPLEDF GGHHPDPNLT YAADLVETMK SGEHDFGAAF DGDGDRNMIL GKHGFFVNPS DSVAVIAANI FSIPYFQQTG VRGFARSMPT SGALDRVASA TKIALYETPT GWKFFGNLMD ASKLSLCGEE SFGTGSDHIR EKDGLWAVLA WLSILATRKQ SVEDILKDHW QKYGRNFFTR YDYEEVEAEG ANKMMKDLEA LMFDRSFVGK QFSANDKVYT VEKADNFEYS DPVDGSISRN QGLRLIFTDG SRIVFRLSGT GSAGATIRLY IDSYEKDVAK INQDPQVMLA PLISIALKVS QLQERTGRTA PTVIT

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