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Recombinant human CSK protein

CAT: 0112-ATGP2842-010Size: 10 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP2842-010Size:10 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CSK is a tyrosine-protein kinase CSK that plays an important role in the regulation of cell growth, differentiation, migration and immune response. Suppresses signaling by various surface receptors, including T-cell receptor (TCR) and B-cell receptor (BCR) by phosphorylating and maintaining inactive several positive effectors such as FYN or LCK.. Recombinant human CSK protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Name Alternative
Tyrosine-protein kinase CSK, Tyrosine-protein kinase CSK, C-Src kinase, Protein-tyrosine kinase CYL, Tyrosine protein kinase CSK
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 95% by SDS-PAGE
Molecular Weight
53.1 kDa (473aa)
Additionnal Information
CSK, Tyrosine-protein kinase CSK, Tyrosine-protein kinase CSK, C-Src kinase, Protein-tyrosine kinase CYL, Tyrosine protein kinase CSK, ATGP2842-10 µg, ATGP2842-20 µg, ATGP2842-50 µg, ATGP2842-100 µg, ATGP2842-250 µg, ATGP2842-500 µg, ATGP2842-1 mg, ATGP2842-10, ATGP2842-20, ATGP2842-50, ATGP2842-100, ATGP2842-250, ATGP2842-500, ATGP2842-1
References & Citations
Braeuninger A., et al. (1991) Proc. Natl. Acad. Sci. u.S.A. 88:10411-10415
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 20% glycerol, 1mM DTT
Scientific Category
Signal Transduction
NCBI Accession Number
NP_001120662.1
Uniprot Accession Number
P41240
Species
Human
AA Sequence
MSAIQAA WPSGTECIAK YNFHGTAEQD LPFCKGDVLT IVAVTKDPNW YKAKNKVGRE GIIPANYVQK REGVKAGTKL SLMPWFHGKI TREQAERLLY PPETGLFLVR ESTNYPGDYT LCVSCDGKVE HYRIMYHASK LSIDEEVYFE NLMQLVEHYT SDADGLCTRL IKPKVMEGTV AAQDEFYRSG WALNMKELKL LQTIGKGEFG DVMLGDYRGN KVAVKCIKND ATAQAFLAEA SVMTQLRHSN LVQLLGVIVE EKGGLYIVTE YMAKGSLVDY LRSRGRSVLG GDCLLKFSLD VCEAMEYLEG NNFVHRDLAA RNVLVSEDNV AKVSDFGLTK EASSTQDTGK LPVKWTAPEA LREKKFSTKS DVWSFGILLW EIYSFGRVPY PRIPLKDVVP RVEKGYKMDA PDGCPPAVYE VMKNCWHLDA AMRPSFLQLR EQLEHIKTHE LHL

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