Products for Research Use Only
RegisterLogin

Recombinant human SMARCA4 protein

CAT: 0112-ATGP2799-100Size: 100 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0112-ATGP2799-100Size:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
SMARCA4 is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Mutations in this gene cause rhabdoid tumor predisposition syndrome type 2. Multiple transcript variants encoding different isoforms have been found for this gene.. Recombinant human SMARCA4 protein, fused to His-tag at N-terminus, was expressed in E. coli.
Product Name Alternative
Transcription activator BRG1 isoform A, BAF190, BAF190A, BRG1, hSNF2b, MRD16, RTPS2, SNF2, SNF2L4, SNF2LB, SWI2
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 80% by SDS-PAGE
Molecular Weight
25kDa (211aa)
Additionnal Information
SMARCA4, Transcription activator BRG1 isoform A, BAF190, BAF190A, BRG1, hSNF2b, MRD16, RTPS2, SNF2, SNF2L4, SNF2LB, SWI2, ATGP2799-10 µg, ATGP2799-20 µg, ATGP2799-50 µg, ATGP2799-100 µg, ATGP2799-250 µg, ATGP2799-500 µg, ATGP2799-1 mg, ATGP2799-10, ATGP2799-20, ATGP2799-50, ATGP2799-100, ATGP2799-250, ATGP2799-500, ATGP2799-1
References & Citations
Dykhuizen, E.C, et al. (2013) Nature 497 (7451), 624-627 ; ; Bai, J., et al. (2013) PLoS ONE 8 (3), E59772
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol
Scientific Category
Neuroscience
NCBI Accession Number
NP_001122321
Uniprot Accession Number
Q9HBD4
Species
Human
AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSDPVEILQ EREYRLQARI AHRIQELENL PGSLAGDLRT KATIELKALR LLNFQRQLRQ EVVVCMRRDT ALETALNAKA YKRSKRQSLR EARITEKLEK QQKIEQERKR RQKHQEYLNS ILQHAKDFKE YHRSVTGKIQ KLTKAVATYH ANTEREQKKE NERIEKERMR RLMAEDEEGY RKLIDQKKDK R

Related Products

CatalogName
TPM0701-500Recombinant human TPMT protein
TPM0701-100Recombinant human TPMT protein
TPD0501-020Recombinant human TPD52L1 protein
SNP0902-500Recombinant human Syntaphilin protein
SNP0901-050Recombinant human SNAP23 protein
SNP0801-020Recombinant human SNAP25 protein
SNP0601-100Recombinant human SNAP25 protein
SNA0901-020Recombinant human SNAPIN protein
SMD0901-500Recombinant human Smad4 protein
RCV0501-020Recombinant human Recoverin protein

Alternative Products

CatalogName
PROTQ9HBD4-20ugHuman SMARCA4 Recombinant Protein
E30P03025BRecombinant Human SMARCA4 Protein
OPCA04343-1MGSMARCA4 Recombinant Protein (Human)
PROTP51532SMARCA4 Human Recombinant Protein
OPCA02798-20UGSMARCA4 Recombinant Protein
MBS140685-01Recombinant Human SMARCA4
rAP-4213SMARCA4 Human Recombinant
TMPH-02217-01SMARCA4 Protein, Human, Recombinant (His)
GTR18881743-01Human SMARCA4 protein
PR12811Recombinant Human SMARCA4 Protein, N-His

Popular Products