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Recombinant human FDFT1 protein

CAT: 0112-ATGP2789-010Size: 10 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP2789-010Size:10 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
FDFT1 is a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene. Recombinant human FDFT1 protein, fused to His-tag at N-terminus, was expressed in E. coli.
Product Name Alternative
Squalene synthase, DGPT, ERG9, SQS, SS
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
0.25 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
35.4 kDa (306aa)
Additionnal Information
FDFT1, Squalene synthase, DGPT, ERG9, SQS, SS, ATGP2789-10 µg, ATGP2789-20 µg, ATGP2789-50 µg, ATGP2789-100 µg, ATGP2789-250 µg, ATGP2789-500 µg, ATGP2789-1 mg, ATGP2789-10, ATGP2789-20, ATGP2789-50, ATGP2789-100, ATGP2789-250, ATGP2789-500, ATGP2789-1
References & Citations
Tansey TR, Shechter I (2000) Biochim. Biophys. Acta 1529 (1-3) : 49-62.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.4M urea
Scientific Category
Metabolism
NCBI Accession Number
NP_004453
Uniprot Accession Number
P37268
Species
Human
AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSMEFVKCL GHPEEFYNLV RFRIGGKRKV MPKMDQDSLS SSLKTCYKYL NQTSRSFAAV IQALDGEMRN AVCIFYLVLR ALDTLEDDMT ISVEKKVPLL HNFHSFLYQP DWRFMESKEK DRQVLEDFPT ISLEFRNLAE KYQTVIADIC RRMGIGMAEF LDKHVTSEQE WDKYCHYVAG LVGIGLSRLF SASEFEDPLV GEDTERANSM GLFLQKTNII RDYLEDQQGG REFWPQEVWS RYVKKLGDFA KPENIDLAVQ CLNELITNAL HHIPDVITYL SRLRNQ

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