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Recombinant human KRT5 protein

CAT: 0112-ATGP2640-020Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP2640-020Size:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
KRT5 is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Mutations in these genes have been associated with a complex of diseases termed epidermolysis bullosa simplex. Recombinant human KRT5 protein, fused to His-tag at N-terminus, was expressed in E. coli
Product Name Alternative
Keratin 5, CK5, DDD, K5, KRT5A
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
64.8 kDa (613aa)
Additionnal Information
KRT5, Keratin 5, CK5, DDD, K5, KRT5A, ATGP2640-10 µg, ATGP2640-20 µg, ATGP2640-50 µg, ATGP2640-100 µg, ATGP2640-250 µg, ATGP2640-500 µg, ATGP2640-1 mg, ATGP2640-10, ATGP2640-20, ATGP2640-50, ATGP2640-100, ATGP2640-250, ATGP2640-500, ATGP2640-1
References & Citations
Nishizawa M., et a.l (2005) Cell Sci. 118:1081-1090..
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.4M urea
Scientific Category
Signal Transduction
NCBI Accession Number
AAH24292
Uniprot Accession Number
P13647
Species
Human
AA Sequence
MSRQSSV SFRSGGSRSF STASAITPSV SRTSFTSVSR SGGGGGGGFG RVSLAGACGV GGYGSRSLYN LGGSKRISIS TSGGSFRNRF GAGAGGGYGF GGGAGSGFGF GGGAGGGFGL GGGAGFGGGF GGPGFPVCPP GGIQEVTVNQ SLLTPLNLQI DPSIQRVRTE EREQIKTLNN KFASFIDKVR FLEQQNKVLD TKWTLLQEQG TKTVRQNLEP LFEQYINNLR RQLDSIVGER GRLDSELRNM QDLVEDFKNK YEDEINKRTT AENEFVMLKK DVDAAYMNKV ELEAKVDALM DEINFMKMFF DAELSQMQTH VSDTSVVLSM DNNRNLDLDS IIAEVKAQYE EIANRSRTEA ESWYQTKYEE LQQTAGRHGD DLRNTKHEIS EMNRMIQRLR AEIDNVKKQC ANLQNAIADA EQRGELALKD ARNKLAELEE ALQKAKQDMA RLLREYQELM NTKLALDVEI ATYRKLLEGE ECRLSGEGVG PVNISVVTSS VSSGYGSGSG YGGGLGGGLG GGLGGGLAGG GSGSYYSSSS GGVGLSGGLS VGGSGFSASS GRGLGVGFGS GGGSSSSVKF VSTTSSSRKS FKS

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