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Recombinant human NRAGE protein

CAT: 0112-ATGP2455-050Size: 50 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP2455-050Size:50 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MAGED1, as known as Melanoma-associated antigen D1, is expressed in almost all normal adult tissues. It has been demonstrated to be involved in the p75 neurotrophin receptor mediated programmed cell death pathway. It has been involved in Prader-Willi syndrome, which includes hyperphagia, repetitive and compulsive behaviors, and cognitive impairment. Recombinant human MAGED1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Product Name Alternative
Melanoma-associated antigen D1 isoform a, DLXIN-1, NRAGE
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.25 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
31.7 kDa (280aa) confirmed by MALDI-TOF
Additionnal Information
NRAGE, Melanoma-associated antigen D1 isoform a, DLXIN-1, NRAGE, ATGP2455-10 µg, ATGP2455-20 µg, ATGP2455-50 µg, ATGP2455-100 µg, ATGP2455-250 µg, ATGP2455-500 µg, ATGP2455-1 mg, ATGP2455-10, ATGP2455-20, ATGP2455-50, ATGP2455-100, ATGP2455-250, ATGP2455-500, ATGP2455-1
References & Citations
Dombret C. et al. (2012) Hum Mol Genet. 21:4703-4717; ; Mouri , . et al. (2012) J Neurosci. 32:4562-4580.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 1mM DTT
Scientific Category
Apoptosis
NCBI Accession Number
NP_001005333
Uniprot Accession Number
Q9Y5V3
Species
Human
AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSLRPSPNS RASQNPGAAQ PRDVALLQER ANKLVKYLML KDYTKVPIKR SEMLRDIIRE YTDVYPEIIE RACFVLEKKF GIQLKEIDKE EHLYILISTP ESLAGILGTT KDTPKLGLLL VILGVIFMNG NRASEAVLWE ALRKMGLRPG VRHPLLGDLR KLLTYEFVKQ KYLDYRRVPN SNPPEYEFLW GLRSYHETSK MKVLRFIAEV QKRDPRDWTA QFMEAADEAL DALDAAAAEA EARAEARTRM GIGDEAVSGP

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