Recombinant human MAP1/MOAP1 protein

CAT: 0112-ATGP2404-500Size: 500 µgDry Ice: NoHazardous: No
CAT#:0112-ATGP2404-500Size:500 µg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Modulator of apoptosis 1, also known as MOAP1, belongs to the PNMA family and contains one BH3-like domain and one RASSF1-binding domain. It is required for death receptor-dependent apoptosis. MOAP1 homodimerizes and associates with the proapoptotic Bax and the prosurvival Bcl-2 and Bcl-X (L) of the Bcl-2 family in vitro and in vivo in mammalian cells. These data suggest that MOAP1 mediates apoptosis through a mechanism that involves binding to Bax. Recombinant human MOAP1 protein, fused to His-tag at N-terminus, was expressed in E. coli.
Product Name Alternative
Modulator of apoptosis 1, MAP-1, PNMA4, Paraneoplastic antigen Ma4
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
41.9 kDa (374aa)
Additionnal Information
MOAP1, Modulator of apoptosis 1, MAP-1, PNMA4, ATGP2404-10 µg, ATGP2404-20 µg, ATGP2404-50 µg, ATGP2404-100 µg, ATGP2404-250 µg, ATGP2404-500 µg, ATGP2404-1 mg, ATGP2404-10, ATGP2404-20, ATGP2404-50, ATGP2404-100, ATGP2404-250, ATGP2404-500, ATGP2404-1
References & Citations
Baksh S., et al. (2005) Mol Cell. 18:637-650.; ; Tan K O., et al. (2001) J Biol Chem. 276:2802-2807.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.4M urea
Scientific Category
Apoptosis
NCBI Accession Number
NP_071434
Uniprot Accession Number
Q96BY2
Species
Human
AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSMTLRLLE DWCRGMDMNP RKALLIAGIS QSCSVAEIEE ALQAGLAPLG EYRLLGRMFR RDENRKVALV GLTAETSHAL VPKEIPGKGG IWRVIFKPPD PDNTFLSRLN EFLAGEGMTV GELSRALGHE NGSLDPEQGM IPEMWAPMLA QALEALQPAL QCLKYKKLRV FSGRESPEPG EEEFGRWMFH TTQMIKAWQV PDVEKRRRLL ESLRGPALDV IRVLKINNPL ITVDECLQAL EEVFGVTDNP RELQVKYLTT YQKDEEKLSA YVLRLEPLLQ KLVQRGAIER DAVNQARLDQ VIAGAVHKTI RRELNLPEDG PAPGFLQLLV LIKDYEAAEE EEALLQAILE GNFT

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