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Recombinant human TIPIN protein

CAT: 0112-ATGP2342-010Size: 10 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP2342-010Size:10 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TIPIN belongs to the CSM3 family. This protein is required for normal progression of S-phase and important for cell survival after DNA damage or replication stress. TIPIN may be specifically required for the ATR-CHEK1 pathway in the replication checkpoint induced by hydroxyurea or ultraviolet light. Recombinant human TIPIN, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Name Alternative
TIMELESS interacting protein, TIMELESS-interacting protein
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
36.9 kDa (324aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
Additionnal Information
TIPIN, TIMELESS interacting protein, TIMELESS-interacting protein, ATGP2342-10 µg, ATGP2342-20 µg, ATGP2342-50 µg, ATGP2342-100 µg, ATGP2342-250 µg, ATGP2342-500 µg, ATGP2342-1 mg, ATGP2342-10, ATGP2342-20, ATGP2342-50, ATGP2342-100, ATGP2342-250, ATGP2342-500, ATGP2342-1
References & Citations
Dheekollu, J., et al. (2011) J. Virol. 85 (12), 5853-5863; ; Kemp, M.G., et al. (2010) J. Biol. Chem. 285 (22), 16562-16571;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Epigenomics (Transcription & Translation)
NCBI Accession Number
NP_060328
Uniprot Accession Number
Q9BVW5
Species
Human
AA Sequence
MLEPQEN GVIDLPDYEH VEDETFPPFP PPASPERQDG EGTEPDEESG NGAPVPVPPK RTVKRNIPKL DAQRLISERG LPALRHVFDK AKFKGKGHEA EDLKMLIRHM EHWAHRLFPK LQFEDFIDRV EYLGSKKEVQ TCLKRIRLDL PILHEDFVSN NDEVAENNEH DVTSTELDPF LTNLSESEMF ASELSRSLTE EQQQRIERNK QLALERRQAK LLSNSQTLGN DMLMNTPRAH TVEEVNTDED QKEESNGLNE DILDNPCNDA IANTLNEEET LLDQSFKNVQ QQLDATSRNI TEAR

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