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Recombinant human TADA3 protein

CAT: 0112-ATGP2312-250Size: 250 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP2312-250Size:250 µg
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Description
Transcriptional adapter 3 isoform a, also known as TATD3, is a subunit of 2 histone acetyltransferase complexes. TATD3 is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. In addition, it associates with the tumor suppressor protein p53 and is required for full activity of p53 and p53-mediated apoptosis. Recombinant human TATD3 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Name Alternative
Transcriptional adapter 3 isoform a, Transcriptional adapter 3 isoform a, ADA3, hADA3, NGG1, TADA3L
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 80% by SDS-PAGE
Molecular Weight
51.3 kDa (455aa)
Additionnal Information
TADA3, Transcriptional adapter 3 isoform a, Transcriptional adapter 3 isoform a, ADA3, hADA3, NGG1, TADA3L, ATGP2312-10 µg, ATGP2312-20 µg, ATGP2312-50 µg, ATGP2312-100 µg, ATGP2312-250 µg, ATGP2312-500 µg, ATGP2312-1 mg, ATGP2312-10, ATGP2312-20, ATGP2312-50, ATGP2312-100, ATGP2312-250, ATGP2312-500, ATGP2312-1
References & Citations
Li CW., et al. (2010) Nucleic Acids Res. 38 (16) :5291-303.; ; Hu Y., et al. (2009) Cancer Invest. 27 (3) :298-306.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 50% glycerol, 2mM DTT
Scientific Category
Epigenomics (Transcription & Translation)
NCBI Accession Number
NP_006345
Uniprot Accession Number
O75528
Species
Human
AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSMSELKDC PLQFHDFKSV DHLKVCPRYT AVLARSEDDG IGIEELDTLQ LELETLLSSA SRRLRVLEAE TQILTDWQDK KGDRRFLKLG RDHELGAPPK HGKPKKQKLE GKAGHGPGPG PGRPKSKNLQ PKIQEYEFTD DPIDVPRIPK NDAPNRFWAS VEPYCADITS EEVRTLEELL KPPEDEAEHY KIPPLGKHYS QRWAQEDLLE EQKDGARAAA VADKKKGLMG PLTELDTKDV DALLKKSEAQ HEQPEDGCPF GALTQRLLQA LVEENIISPM EDSPIPDMSG KESGADGAST SPRNQNKPFS VPHTKSLESR IKEELIAQGL LESEDRPAED SEDEVLAELR KRQAELKALS AHNRTKKHDL LRLAKEEVSR QELRQRVRMA DNEVMDAFRK IMAARQKKRT PTKKEKDQAW KTLKERESIL KLLDG