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Recombinant human UPRT protein

CAT: 0112-ATGP2309-020Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP2309-020Size:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
UPRT is a uracil phosphoribosyltransferase, which catalyzes the conversion of uracil and 5-phosphoribosyl-1-R-diphosphate to uridine monophosphate (uMP) . This reaction is an important part of nucleotide metabolism, specifically the pyrimidine salvage pathway. The enzyme localizes to the nucleus and cytoplasm. The protein is a potential target for rational design of drugs to treat parasitic infections and cancer. Recombinant human uPRT protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Name Alternative
Uracil phosphoribosyltransferase homolog, uracil phosphoribosyltransferase (FuR1) homolog (S.cerevisiae), FuR1, RP11-311P8.3, uPP
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
36.2 kDa (332aa) confirmed by MALDI-TOF
Additionnal Information
UPRT, uracil phosphoribosyltransferase homolog, uracil phosphoribosyltransferase (FuR1) homolog (S.cerevisiae), FuR1, RP11-311P8.3, uPP, ATGP2309-10 µg, ATGP2309-20 µg, ATGP2309-50 µg, ATGP2309-100 µg, ATGP2309-250 µg, ATGP2309-500 µg, ATGP2309-1 mg, ATGP2309-10, ATGP2309-20, ATGP2309-50, ATGP2309-100, ATGP2309-250, ATGP2309-500, ATGP2309-1
References & Citations
T. Selwood and E. K. Jaffe. (2011) Arch. Biochem. Biophys. 519 (2) : 131-43.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 20% glycerol, 1mM DTT
Scientific Category
Epigenomics (Transcription & Translation)
NCBI Accession Number
NP_659489
Uniprot Accession Number
Q96BW1
Species
Human
AA Sequence
MATELQC PDSMPCHNQQ VNSASTPSPE QLRPGDLILD HAGGNRASRA KVILLTGYAH SSLPAELDSG ACGGSSLNSE GNSGSGDSSS YDAPAGNSFL EDCELSRQIG AQLKLLPMND QIRELQTIIR DKTASRGDFM FSADRLIRLV VEEGLNQLPY KECMVTTPTG YKYEGVKFEK GNCGVSIMRS GEAMEQGLRD CCRSIRIGKI LIQSDEETQR AKVYYAKFPP DIYRRKVLLM YPILSTGNTV IEAVKVLIEH GVQPSVIILL SLFSTPHGAK SIIQEFPEIT ILTTEVHPVA PTHFGQKYFG TD

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