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Recombinant human TEF protein

CAT: 0112-ATGP2170-100Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP2170-100Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Thyrotroph embryonic factor isoform 1, also known as TEF, is a 303 amino acid nuclear transcription factor that belongs to the bZIP (basic region/leucine zipper) family and PAR (proline and acidic amino acid-rich) subfamily. TEF binds DNA as either a homodimer or heterodimer, and is known to transactivate the TSH beta promoter. TEF accumulates according to a robust circadian rhythm and has also been found to inhibit cell growth by down-regulating beta chain expression of cytokine receptors. Recombinant human TEF protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Name Alternative
Thyrotroph embryonic factor isoform 1, KIAA1655, Thyrotroph embryonic factor
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.25 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
35.6 kDa (326aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
Additionnal Information
TEF, Thyrotroph embryonic factor isoform 1, KIAA1655, Thyrotroph embryonic factor, ATGP2170-10 µg, ATGP2170-20 µg, ATGP2170-50 µg, ATGP2170-100 µg, ATGP2170-250 µg, ATGP2170-500 µg, ATGP2170-1 mg, ATGP2170-10, ATGP2170-20, ATGP2170-50, ATGP2170-100, ATGP2170-250, ATGP2170-500, ATGP2170-1
References & Citations
Khatib Z A., et al. (1994) Genomics. 23:344-351; ; Drolet D W., et al. (1991) Genes Dev. 5:1739-1753.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol
Scientific Category
Epigenomics (Transcription & Translation)
NCBI Accession Number
NP_003207
Uniprot Accession Number
Q10587
Species
Human
AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSMSDAGGG KKPPVDPQAG PGPGPGRAAG ERGLSGSFPL VLKKLMENPP REARLDKEKG KEKLEEDEAA AASTMAVSAS LMPPIWDKTI PYDGESFHLE YMDLDEFLLE NGIPASPTHL AHNLLLPVAE LEGKESASSS TASPPSSSTA IFQPSETVSS TESSLEKERE TPSPIDPNCV EVDVNFNPDP ADLVLSSVPG GELFNPRKHK FAEEDLKPQP MIKKAKKVFV PDEQKDEKYW TRRKKNNVAA KRSRDARRLK ENQITIRAAF LEKENTALRT EVAELRKEVG KCKTIVSKYE TKYGPL

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