Products for Research Use Only
RegisterLogin

Recombinant human GIP protein

CAT: 0112-ATGP2061-010Size: 10 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0112-ATGP2061-010Size:10 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
GIP, also known as glucose-dependent insulinotropic polypeptide, is an important insulin-releasing hormone of the enteroinsular axis that has a functional profile of possible therapeutic value for type 2 diabetes. This protein is an important incretin hormone released into the circulation from endocrine K-cells of the duodenum and jejunum after ingestion of food1. It was evaluated for their ability to elevate cellular cAMP production and stimulate insulin secretion. It also promotes plasma triglyceride clearance in response to oral fat loading. In liver, GIP has been shown to enhance insulin-dependent inhibition of glycogenolysis. Recombinant human GIP protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Product Name Alternative
Gastric inhibitory polypeptide, Glucose-dependent insulinotropic polypeptide, Gastric Inhibitory Peptide
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.25 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
17.3 kDa (155aa) confirmed by MALDI-TOF
Additionnal Information
GIP, Gastric inhibitory polypeptide, Glucose-dependent insulinotropic polypeptide, Gastric Inhibitory Peptide, ATGP2061-10 µg, ATGP2061-20 µg, ATGP2061-50 µg, ATGP2061-100 µg, ATGP2061-250 µg, ATGP2061-500 µg, ATGP2061-1 mg, ATGP2061-10, ATGP2061-20, ATGP2061-50, ATGP2061-100, ATGP2061-250, ATGP2061-500, ATGP2061-1
References & Citations
O'Harte FP. et al. (1999) Diabetes. 48:758-765; ; Gault VA. et al. (2002) Biosci Rep. 22:523-528.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 50% glycerol 0.1M NaCl, 2mM DTT
Scientific Category
Signal Transduction
NCBI Accession Number
AAH69100
Uniprot Accession Number
P09681
Species
Human
AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSEKKEGHF SALPSLPVGS HAKVSSPQPR GPRYAEGTFI SDYSIAMDKI HQQDFVNWLL AQKGKKNDWK HNITQREARA LELAGQANRK EEEAVEPQSS PAKNPSDEDL LRDLLIQELL ACLLDQTNLC RLRSR

Related Products

CatalogName
TPM0701-500Recombinant human TPMT protein
TPM0701-100Recombinant human TPMT protein
TPD0501-020Recombinant human TPD52L1 protein
SNP0902-500Recombinant human Syntaphilin protein
SNP0901-050Recombinant human SNAP23 protein
SNP0801-020Recombinant human SNAP25 protein
SNP0601-100Recombinant human SNAP25 protein
SNA0901-020Recombinant human SNAPIN protein
SMD0901-500Recombinant human Smad4 protein
RCV0501-020Recombinant human Recoverin protein

Alternative Products

CatalogName
ARP2794-01Recombinant Human Leptin Human Recombinant Protein
MBS1561940-01Recombinant Human WAS protein
PPT-16033Human WAS Recombinant Protein
TP727635Human Recombinant Protein

Popular Products