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Recombinant human ARC protein

CAT: 0112-ATGP2016-250Size: 250 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP2016-250Size:250 µg
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Description
Activity-regulated cytoskeleton-associated protein, also known as ARC, is required for consolidation of synaptic plasticity as well as formation of long-term memory. This protein regulates endocytosis of AMPA receptors in response to synaptic activity. This protein required for homeostatic synaptic scaling of AMPA receptors. This protein plays a role in the regulation of cell morphology and cytoskeletal organization. Recombinant human ARC protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Name Alternative
Activity-regulated cytoskeleton-associated protein, Arg3.1, KIAA0278
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
47.4 kDa (416aa) confirmed by MALDI-TOF
Additionnal Information
ARC, Activity-regulated cytoskeleton-associated protein, Arg3.1, KIAA0278, ATGP2016-10 µg, ATGP2016-20 µg, ATGP2016-50 µg, ATGP2016-100 µg, ATGP2016-250 µg, ATGP2016-500 µg, ATGP2016-1 mg, ATGP2016-10, ATGP2016-20, ATGP2016-50, ATGP2016-100, ATGP2016-250, ATGP2016-500, ATGP2016-1
References & Citations
Nagase T., et al. (1996) DNA Res. 3:321-329
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT
Scientific Category
Neuroscience
NCBI Accession Number
NP_056008
Uniprot Accession Number
Q7LC44
Species
Human
AA Sequence
MGSSHHHHHH SSGLVPRGSH MELDHRTSGG LHAYPGPRGG QVAKPNVILQ IGKCRAEMLE HVRRTHRHLL AEVSKQVERE LKGLHRSVGK LESNLDGYVP TSDSQRWKKS IKACLCRCQE TIANLERWVK REMHVWREVF YRLERWADRL ESTGGKYPVG SESARHTVSV GVGGPESYCH EADGYDYTVS PYAITPPPAA GELPGQEPAE AQQYQPWVPG EDGQPSPGVD TQIFEDPREF LSHLEEYLRQ VGGSEEYWLS QIQNHMNGPA KKWWEFKQGS VKNWVEFKKE FLQYSEGTLS REAIQRELDL PQKQGEPLDQ FLWRKRDLYQ TLYVDADEEE IIQYVVGTLQ PKLKRFLRHP LPKTLEQLIQ RGMEVQDDLE QAAEPAGPHL PVEDEAETLT PAPNSESVAS DRTQPE

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