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Recombinant human ERLIN2 protein

CAT: 0112-ATGP1782-500Size: 500 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP1782-500Size:500 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ERLIN2, also known as SPFH2, is SPFH domain-containing proteins that belong to the prohibitin family. Also, this protein is a ubiquitously expressed 339 amino acid protein that belongs to the band 7/mec-2 family. Localized to lipid raft-like domains in the membrane of the endoplasmic reticulum (ER), ERLIN2 plays a crucial role in the ER-associated degradation (ERAD) pathway that removes metabolically regulated and aberrant proteins from the ER. Recombinant human ERLIN2 protein, fused to His-tag at N-terminus, was expressed in E. coli.
Product Name Alternative
Erlin-2, C8orf2, Erlin-2, NET32, SPFH2, SPG18
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 95% by SDS-PAGE
Molecular Weight
37.8 kDa (338aa)
Additionnal Information
ERLIN2, Erlin-2, C8orf2, Erlin-2, NET32, SPFH2, SPG18, ATGP1782-10 µg, ATGP1782-20 µg, ATGP1782-50 µg, ATGP1782-100 µg, ATGP1782-250 µg, ATGP1782-500 µg, ATGP1782-1 mg, ATGP1782-10, ATGP1782-20, ATGP1782-50, ATGP1782-100, ATGP1782-250, ATGP1782-500, ATGP1782-1
References & Citations
Browman D T., et al. (2006) J Cell Sci. 119:3149-60.; ; Ikeqawa S., et al. (1999) Cytogenet Cell Genet. 85:227-231.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 2M urea, 20% glycerol
Scientific Category
Signal Transduction
NCBI Accession Number
NP_009106
Uniprot Accession Number
O94905
Species
Human
AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSKIEEGHI GVYYRGGALL TSTSGPGFHL MLPFITSYKS VQTTLQTDEV KNVPCGTSGG VMIYFDRIEV VNFLVPNAVY DIVKNYTADY DKALIFNKIH HELNQFCSVH TLQEVYIELF DQIDENLKLA LQQDLTSMAP GLVIQAVRVT KPNIPEAIRR NYELMESEKT KLLIAAQKQK VVEKEAETER KKALIEAEKV AQVAEITYGQ KVMEKETEKK ISEIEDAAFL AREKAKADAE CYTAMKIAEA NKLKLTPEYL QLMKYKAIAS NSKIYFGKDI PNMFMDSAGS VSKQFEGLAD KLSFGLEDEP LETATKEN

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