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Recombinant human NDUFA2 protein

CAT: 0112-ATGP1770-010Size: 10 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP1770-010Size:10 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NDuFA2 is a subunit of the hydrophobic protein fraction of the NADH:ubiquinone oxidoreductase (complex 1), the first enzyme complex in the electron transport chain located in the inner mitochondrial membrane, and may be involved in regulating complex I activity or its assembly via assistance in redox. Mutations in this protein are associated with Leigh syndrome, an early-onset progressive neurodegenerative disorder. Recombinant human NDuFA2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Name Alternative
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2, Complex I-B8, CI-B8, NADH-ubiquinone oxidoreductase B8 subunit, NADH:ubiquinone oxidoreductase subunit A2
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 95% by SDS-PAGE
Molecular Weight
13.3 kDa (122aa) confirmed by MALDI-TOF
Additionnal Information
NDUFA2, NADH dehydrogenase 1 alpha subcomplex, B8, CD14, CIB8, ATGP1770-10 µg, ATGP1770-20 µg, ATGP1770-50 µg, ATGP1770-100 µg, ATGP1770-250 µg, ATGP1770-500 µg, ATGP1770-1 mg, ATGP1770-10, ATGP1770-20, ATGP1770-50, ATGP1770-100, ATGP1770-250, ATGP1770-500, ATGP1770-1
References & Citations
Murray, J., et al. (2003) J. Biol. Chem. 278 (16), 13619-13622; ; Loeffen, J.L.., et al. (1998) Biochem. Biophys. Res. Commun. 253 (2), 415-422.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol,1mM DTT
Scientific Category
Metabolism
NCBI Accession Number
NP_002479
Uniprot Accession Number
O43678
Species
Human
AA Sequence
MAAAAAS RGVGAKLGLR EIRIHLCQRS PGSQGVRDFI EKRYVELKKA NPDLPILIRE CSDVQPKLWA RYAFGQETNV PLNNFSADQV TRALENVLSG KA

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