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Recombinant human ABI3 protein

CAT: 0112-ATGP1733-004Size: 4 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP1733-004Size:4 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ABI3, also as known as ABI gene family member 3, belongs to the ABI family. This protein is a member of an adaptor protein family. Members of this family encode proteins containing a homeobox homology domain, proline rich region and Src-homology 3 (SH3) domain. The Abi family members are thought to negatively regulate cell growth and transformation, including cellular transformation through v-Abl as well as mediate cell motility by regulating actin polymerization in lamellipodia and filopodia. ABI3 inhibits ectopic metastasis of tumor cells as well as cell migration. This may be accomplished through interaction with p21-activated kinase.
Product Name Alternative
ABI family member 3, ABI family, member 3, NESH, SSH3BP3
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
41.4 kDa (389aa)
Additionnal Information
ABI3, ABI family member 3, ABI family, member 3, NESH, SSH3BP3, ATGP1733-10 µg, ATGP1733-20 µg, ATGP1733-50 µg, ATGP1733-100 µg, ATGP1733-250 µg, ATGP1733-500 µg, ATGP1733-1 mg, ATGP1733-10, ATGP1733-20, ATGP1733-50, ATGP1733-100, ATGP1733-250, ATGP1733-500, ATGP1733-1
References & Citations
Ichigotani Y., et al. (2002) Cancer Res. 62:2215-2219; ; Miyazaki K, et al. (2000) Biochim Biophys Acta 1493 (1-2) : 237-41.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol
Scientific Category
Cancer
NCBI Accession Number
NP_057512
Uniprot Accession Number
Q9P2A4
Species
Human
AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSMAELQQL QEFEIPTGRE ALRGNHSALL RVADYCEDNY VQATDKRKAL EETMAFTTQA LASVAYQVGN LAGHTLRMLD LQGAALRQVE ARVSTLGQMV NMHMEKVARR EIGTLATVQR LPPGQKVIAP ENLPPLTPYC RRPLNFGCLD DIGHGIKDLS TQLSRTGTLS RKSIKAPATP ASATLGRPPR IPEPVHLPVV PDGRLSAASS ASSLASAGSA EGVGGAPTPK GQAAPPAPPL PSSLDPPPPP AAVEVFQRPP TLEELSPPPP DEELPLPLDL PPPPPLDGDE LGLPPPPPGF GPDEPSWVPA SYLEKVVTLY PYTSQKDNEL SFSEGTVICV TRRYSDGWCE GVSSEGTGFF PGNYVEPSC

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