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Recombinant human JAM-C protein

CAT: 0112-ATGP1723-004Size: 4 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP1723-004Size:4 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. JAM3 is localized in the tight junctions between high endothelial cells. unlike other proteins in this family, this protein is unable to adhere to leukocyte cell lines and only forms weak homotypic interactions. JAM3 is a member of the junctional adhesion molecule protein family and acts as a receptor for another member of this family. Recombinant human JAM3 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Name Alternative
Junctional adhesion molecule C, Junctional adhesion molecule 3, JAM-C, JAMC
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.25 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
26 kDa (234aa) confirmed by MALDI-TOF
Additionnal Information
JAM-C, Junctional adhesion molecule C, Junctional adhesion molecule 3, JAM-C, JAMC, ATGP1723-10 µg, ATGP1723-20 µg, ATGP1723-50 µg, ATGP1723-100 µg, ATGP1723-250 µg, ATGP1723-500 µg, ATGP1723-1 mg, ATGP1723-10, ATGP1723-20, ATGP1723-50, ATGP1723-100, ATGP1723-250, ATGP1723-500, ATGP1723-1
References & Citations
Santoso S., et al. (2002) . J Exp Med. 2; ;196 (5) :679-91.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 50% glycerol, 2mM EDTA, 5mM DTT
Scientific Category
Signal Transduction
NCBI Accession Number
NP_116190
Uniprot Accession Number
Q9BX67
Species
Human
AA Sequence
VNLKSS NRTPVVQEFE SVELSCIITD SQTSDPRIEW KKIQDEQTTY VFFDNKIQGD LAGRAEILGK TSLKIWNVTR RDSALYRCEV VARNDRKEID EIVIELTVQV KPVTPVCRVP KAVPVGKMAT LHCQESEGHP RPHYSWYRND VPLPTDSRAN PRFRNSSFHL NSETGTLVFT AVHKDDSGQY YCIASNDAGS ARCEEQEMEV YDLN

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