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Recombinant human RBBP4 protein

CAT: 0112-ATGP1656-500Size: 500 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP1656-500Size:500 µg
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Description
Retinoblastoma binding protein 4, also known as RBBP4, is a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. It is present in protein complexes involved in histone acetylation and chromatin assembly. RBBP4 is also part of co-repressor complexes, which is an integral component of transcriptional silencing. It is found among several cellular proteins that bind directly to retinoblastoma protein to regulate cell proliferation. Recombinant human RBBP4 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Name Alternative
Retinoblastoma binding protein 4, NuRF55, RBAP48
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
50.2 kDa (449aa)
Additionnal Information
RBBP4, Retinoblastoma binding protein 4, NuRF55, RBAP48, ATGP1656-10 µg, ATGP1656-20 µg, ATGP1656-50 µg, ATGP1656-100 µg, ATGP1656-250 µg, ATGP1656-500 µg, ATGP1656-1 mg, ATGP1656-10, ATGP1656-20, ATGP1656-50, ATGP1656-100, ATGP1656-250, ATGP1656-500, ATGP1656-1
References & Citations
Qian YW., et al. (1993) Nature. 364 (6438) : 648-52; ; Nicolas E., et al. (2001) Nucleic Acids Res. 29 (15) : 3131-6.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol,1mM EDTA
Scientific Category
Epigenomics (Transcription & Translation)
NCBI Accession Number
NP_005601
Uniprot Accession Number
Q09028
Species
Human
AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSHMADKEA AFDDAVEERV INEEYKIWKK NTPFLYDLVM THALEWPSLT AQWLPDVTRP EGKDFSIHRL VLGTHTSDEQ NHLVIASVQL PNDDAQFDAS HYDSEKGEFG GFGSVSGKIE IEIKINHEGE VNRARYMPQN PCIIATKTPS SDVLVFDYTK HPSKPDPSGE CNPDLRLRGH QKEGYGLSWN PNLSGHLLSA SDDHTICLWD ISAVPKEGKV VDAKTIFTGH TAVVEDVSWH LLHESLFGSV ADDQKLMIWD TRSNNTSKPS HSVDAHTAEV NCLSFNPYSE FILATGSADK TVALWDLRNL KLKLHSFESH KDEIFQVQWS PHNETILASS GTDRRLNVWD LSKIGEEQSP EDAEDGPPEL LFIHGGHTAK ISDFSWNPNE PWVICSVSED NIMQVWQMAE NIYNDEDPEG SVDPEGQGS