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Recombinant human APIP protein

CAT: 0112-ATGP1614-100Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP1614-100Size:100 µg
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Description
APIP, also known as probable methylthioribulose-1-phosphate dehydratase, catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2, 3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) . It has an anti-apoptotic function and prevents muscle ischemic damage. This protein inhibits the cytochrome c-dependent and APAF1-mediated cell death. Recombinant human APIP protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Product Name Alternative
Probable methylthioribulose-1-phosphate dehydratase, APIP2, CGI-29, CGI29, dJ179L10.2, MMRP19
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
29.7 kDa (266aa) confirmed by MALDI-TOF
Additionnal Information
APIP, Probable methylthioribulose-1-phosphate dehydratase, APIP2, CGI-29, CGI29, dJ179L10.2, MMRP19, ATGP1614-10 µg, ATGP1614-20 µg, ATGP1614-50 µg, ATGP1614-100 µg, ATGP1614-250 µg, ATGP1614-500 µg, ATGP1614-1 mg, ATGP1614-10, ATGP1614-20, ATGP1614-50, ATGP1614-100, ATGP1614-250, ATGP1614-500, ATGP1614-1
References & Citations
Cho D.-H., et al. (2004) J. Biol. Chem. 279:39942-39950; ; Lai C.-H., et al. (2000) Genome Res. 10:703-713
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 1mM DTT
Scientific Category
Apoptosis
NCBI Accession Number
NP_057041
Uniprot Accession Number
Q96GX9
Species
Human
AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSHMSGCDA REGDCCSRRC GAQDKEHPRY LIPELCKQFY HLGWVTGTGG GISLKHGDEI YIAPSGVQKE RIQPEDMFVC DINEKDISGP SPSKKLKKSQ CTPLFMNAYT MRGAGAVIHT HSKAAVMATL LFPGREFKIT HQEMIKGIKK CTSGGYYRYD DMLVVPIIEN TPEEKDLKDR MAHAMNEYPD SCAVLVRRHG VYVWGETWEK AKTMCECYDY LFDIAVSMKK VGLDPSQLPV GENGIV

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