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Recombinant human THAP1 protein

CAT: 0112-ATGP1517-100Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP1517-100Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
THAP domain-containing protein 1, also known as THAP1, is a 213 amino acid protein that localizes to the nucleoplasm and contains one THAPtype zinc finger, a conserved DNA-binding domain. It is a DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression. THAP1 may also have pro-apoptopic activity by potentiating both serum-withdrawal and TNF-induced apoptosis. Recombinant human THAP1protein, fused to His-tag at N-terminus, was expressed in E. coli.
Product Name Alternative
THAP domain-containing protein 1, DYT6
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
27.5 kDa (237aa)
Additionnal Information
THAP1, THAP domain-containing protein 1, DYT6, ATGP1517-10 µg, ATGP1517-20 µg, ATGP1517-50 µg, ATGP1517-100 µg, ATGP1517-250 µg, ATGP1517-500 µg, ATGP1517-1 mg, ATGP1517-10, ATGP1517-20, ATGP1517-50, ATGP1517-100, ATGP1517-250, ATGP1517-500, ATGP1517-1
References & Citations
Roussigne M., et al. (2003) Oncogene 22:2432-2442.; ; Clouaire T., et al. (2005) Proc Natl Acad Sci. 102:6907-6912.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 2M urea, 10% glycerol, 1mM DTT, 0.2M NaCl
Scientific Category
Apoptosis
NCBI Accession Number
NP_060575
Uniprot Accession Number
Q9NVV9
Species
Human
AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSHMVQSCS AYGCKNRYDK DKPVSFHKFP LTRPSLCKEW EAAVRRKNFK PTKYSSICSE HFTPDCFKRE CNNKLLKENA VPTIFLCTEP HDKKEDLLEP QEQLPPPPLP PPVSQVDAAI GLLMPPLQTP VNLSVFCDHN YTVEDTMHQR KRIHQLEQQV EKLRKKLKTA QQRCRRQERQ LEKLKEVVHF QKEKDDVSER GYVILPNDYF EIVEVPA

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