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Recombinant human PBK protein

CAT: 0112-ATGP1437-020Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP1437-020Size:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Lymphokine-activated killer T-cell-originated protein kinase, also known as PBK, is a serine/threonine kinase related to the dual specific mitogen-activated protein kinase (MAPKK) family. PBK is abundant in placenta and absent from adult brain tissue. A PDZ domain in the tumor suppressor protein Dlg can coordinate with the T/SXV motif of PBK. This protein may be involved in the activation of lymphoid cells and support testicular functions, with a suggested role in the process of spermatogenesis. Recombinant human PBK protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Name Alternative
Lymphokine-activated killer T-cell-originated protein kinase, CT84, Nori-3, SPK, TOPK
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 95% by SDS-PAGE
Molecular Weight
38.6 kDa (346aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
Additionnal Information
PBK, Lymphokine-activated killer T-cell-originated protein kinase, CT84, Nori-3, SPK, TOPK, ATGP1437-10 µg, ATGP1437-20 µg, ATGP1437-50 µg, ATGP1437-100 µg, ATGP1437-250 µg, ATGP1437-500 µg, ATGP1437-1 mg, ATGP1437-10, ATGP1437-20, ATGP1437-50, ATGP1437-100, ATGP1437-250, ATGP1437-500, ATGP1437-1
References & Citations
Abe Y., et al. (2000) J Biol Chem. 275:21525-21531.; ; Dougherty J D., et al. (2005) J Neurosci. 25:10773-10785.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol, 0.1M NaCl
Scientific Category
Cell Cycle
NCBI Accession Number
NP_060962
Uniprot Accession Number
Q96KB5
Species
Human
AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSHMEGISN FKTPSKLSEK KKSVLCSTPT INIPASPFMQ KLGFGTGVNV YLMKRSPRGL SHSPWAVKKI NPICNDHYRS VYQKRLMDEA KILKSLHHPN IVGYRAFTEA NDGSLCLAME YGGEKSLNDL IEERYKASQD PFPAAIILKV ALNMARGLKY LHQEKKLLHG DIKSSNVVIK GDFETIKICD VGVSLPLDEN MTVTDPEACY IGTEPWKPKE AVEENGVITD KADIFAFGLT LWEMMTLSIP HINLSNDDDD EDKTFDESDF DDEAYYAALG TRPPINMEEL DESYQKVIEL FSVCTNEDPK DRPSAAHIVE ALETDV

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