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Recombinant human IkB-beta protein

CAT: 0112-ATGP1428-020Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP1428-020Size:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NFKBIB, also known as NF-kappa-B inhibitor beta, belongs to the NF-kappa-B inhibitor family, which inhibit NF-kappa-B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B, which translocates to the nucleus to function as a transcription factor. Recombinant human NFKBIB protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Product Name Alternative
NF-kappa-B inhibitor beta, IKBB, TRIP9
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
40.3 kDa (380aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
Additionnal Information
IkB-b, NF-kappa-B inhibitor beta, IKBB, TRIP9, ATGP1428-10 µg, ATGP1428-20 µg, ATGP1428-50 µg, ATGP1428-100 µg, ATGP1428-250 µg, ATGP1428-500 µg, ATGP1428-1 mg, ATGP1428-10, ATGP1428-20, ATGP1428-50, ATGP1428-100, ATGP1428-250, ATGP1428-500, ATGP1428-1
References & Citations
Fenwick C., et al. (2000) Science. 287:869-873; ; DiDonato J.A., et al. (1996) Mol. Cell. Biol. 16:1295-1304
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 1mM DTT
Scientific Category
Signal Transduction
NCBI Accession Number
NP_002494
Uniprot Accession Number
Q15653
Species
Human
AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSHMAGVAC LGKAADADEW CDSGLGSLGP DAAAPGGPGL GAELGPGLSW APLVFGYVTE DGDTALHLAV IHQHEPFLDF LLGFSAGTEY MDLQNDLGQT ALHLAAILGE TSTVEKLYAA GAGLCVAERR GHTALHLACR VGAHACARAL LQPRPRRPRE APDTYLAQGP DRTPDTNHTP VALYPDSDLE KEEEESEEDW KLQLEAENYE GHTPLHVAVI HKDVEMVRLL RDAGADLDKP EPTCGRSPLH LAVEAQAADV LELLLRAGAN PAARMYGGRT PLGSAMLRPN PILARLLRAH GAPEPEGEDE KSGPCSSSSD SDSGDEGDEY DDIVVHSSRS QTRLPPTPAS KPLPDDPRPV

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