Recombinant human DUSP17/DUSP19 protein

CAT: 0112-ATGP1317-250Size: 250 µgDry Ice: NoHazardous: No
CAT#:0112-ATGP1317-250Size:250 µg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Dual specificity phosphatase 19, also known as DuSP19, is a member of the dual specificity protein phosphatase subfamily. DuSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. They have been implicated as major modulators of critical signaling pathways. DuSP19 is a protein phosphatase which functions as a stress-activated protein kinase pathway-regulating phosphatase. DuSP19 contains a variation of the consensus DuSP C-terminal catalytic domain, with the last serine residue replaced by alanine, and lacks the N-terminal CH2 domain found in the MKP class of DuSPs. Recombinant human DuSP19 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Name Alternative
Dual specificity phosphatase 19, DuSP17, SKRP1, TS-DSP1, Dual specificity phosphatase TS-DSP1, Low molecular weight dual specificity phosphatase 3, LMW-DSP3, Protein phosphatase SKRP1, Stress-activated protein kinase pathway-regulating phosphatase 1, SAPK pathway-regulating phosphatase 1, LMWDSP3
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
19.4 kDa (176aa) confirmed by MALDI-TOF
Additionnal Information
DuSP19, Dual specificity phosphatase 19, DuSP17, SKRP1, TS-DSP1, ATGP1317-10 µg, ATGP1317-20 µg, ATGP1317-50 µg, ATGP1317-100 µg, ATGP1317-250 µg, ATGP1317-500 µg, ATGP1317-1 mg, ATGP1317-10, ATGP1317-20, ATGP1317-50, ATGP1317-100, ATGP1317-250, ATGP1317-500, ATGP1317-1
References & Citations
Cheng H., et al. (2003) Int J BoiChem Cell Biol. 35 (2) :226-34.; ; Zama Takeru., et al. (2002) J Boil Chem. 277 (26) :23909-18.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 30% glycerol, 0.1M NaCl
Scientific Category
Enzymes & Proteases
NCBI Accession Number
NP_543152
Uniprot Accession Number
Q8WTR2
Species
Human
AA Sequence
QVGVIKP WLLLGSQDAA HDLDTLKKNK VTHILNVAYG VENAFLSDFT YKSISILDLP ETNILSYFPE CFEFIEEAKR KDGVVLVHCN AGVSRAAAIV IGFLMNSEQT SFTSAFSLVK NARPSICPNS GFMEQLRTYQ EGKESNKCDR IQENSS

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