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Recombinant human STAR protein

CAT: 0112-ATGP1292-020Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP1292-020Size:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
STAR, also known as steroidogenic acute regulatory protein, appears to mediate the rapid increase in pregnenolone synthesis stimulated by tropic hormones. It increases pregnenolone synthesis more than four-fold and a major STAR transcript of 1. 6 kb is found in ovary and testis. During ongoing growth and differentiation of the follicle of the ovary, the immunoreactivity of it tends to shift from the granulosa cells of early antral follicles to the theca cell layers in the adult. Recombinant human STAR protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Product Name Alternative
Steroidogenic acute regulatory protein mitochondrial, Steroidogenic acute regulatory protein, mitochondrial
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
27.1 kDa (243aa) confirmed by MALDI-TOF
Additionnal Information
STAR, Steroidogenic acute regulatory protein mitochondrial, Steroidogenic acute regulatory protein, mitochondrial, ATGP1292-10 µg, ATGP1292-20 µg, ATGP1292-50 µg, ATGP1292-100 µg, ATGP1292-250 µg, ATGP1292-500 µg, ATGP1292-1 mg, ATGP1292-10, ATGP1292-20, ATGP1292-50, ATGP1292-100, ATGP1292-250, ATGP1292-500, ATGP1292-1
References & Citations
Borthwick F. et al. (2009) FEBS Lett. 583:1147-1153.; ; Mikhaylova I.V. et al. (2008) J. Endocrinol.199: 435-444.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 2mM DTT
Scientific Category
Cancer
NCBI Accession Number
NP_000340.2
Uniprot Accession Number
P49675
Species
Human
AA Sequence
EETLYSDQE LAYLQQGEEA MQKALGILSN QEGWKKESQQ DNGDKVMSKV VPDVGKVFRL EVVVDQPMER LYEELVERME AMGEWNPNVK EIKVLQKIGK DTFITHELAA EAAGNLVGPR DFVSVRCAKR RGSTCVLAGM ATDFGNMPEQ KGVIRAEHGP TCMVLHPLAG SPSKTKLTWL LSIDLKGWLP KSIINQVLSQ TQVDFANHLR KRLESHPASE ARC

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