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Recombinant human DNAJB8 protein

CAT: 0112-ATGP1265-100Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP1265-100Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DNAJB8, also known as dnaJ homolog subfamily B member 8, is superior suppressors of aggregation and toxicity of disease-associated polyglutamine proteins. DNAJB8 is (de) acetylated at two conserved C-terminal lysines that are not involved in substrate binding, but do play a role in suppressing protein aggregation. Recombinant human DNAJB8 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Product Name Alternative
DnaJ homolog subfamily B member 8
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.25 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
27.8 kDa (252aa) confirmed by MALDI-TOF
Additionnal Information
DNAJB8, DnaJ homolog subfamily B member 8, ATGP1265-10 µg, ATGP1265-20 µg, ATGP1265-50 µg, ATGP1265-100 µg, ATGP1265-250 µg, ATGP1265-500 µg, ATGP1265-1 mg, ATGP1265-10, ATGP1265-20, ATGP1265-50, ATGP1265-100, ATGP1265-250, ATGP1265-500, ATGP1265-1
References & Citations
Hageman J., et al. (2010) Mol Cell. 37 (3) :355-69.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 40% glycerol, 0.15M NaCl, 1mM DTT
Scientific Category
Heat Shock Proteins
NCBI Accession Number
NP_699161
Uniprot Accession Number
Q8NHS0
Species
Human
AA Sequence
MGSSHHHHHH SSGLVPRGSH MANYYEVLGV QASASPEDIK KAYRKLALRW HPDKNPDNKE EAEKKFKLVS EAYEVLSDSK KRSLYDRAGC DSWRAGGGAS TPYHSPFDTG YTFRNPEDIF REFFGGLDPF SFEFWDSPFN SDRGGRGHGL RGAFSAGFGE FPAFMEAFSS FNMLGCSGGS HTTFSSTSFG GSSSGSSGFK SVMSSTEMIN GHKVTTKRIV ENGQERVEVE EDGQLKSVTV NGKEQLKWMD SK

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