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Recombinant human AIP protein

CAT: 0112-ATGP1137-500Size: 500 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP1137-500Size:500 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Aryl hydrocarbon receptor (AHR) interacting protein, also known as AIP, may play a positive role in AHR-mediated (aromatic hydrocarbon receptor) signaling, possibly by influencing its receptivity for ligand and/or its nuclear targeting. It is a Cellular negative regulator of the hepatitis B virus (HBV) X protein. Also, AIP is a ubiquitously expressed protein, binds to HSP 90 and AHR through a highly conserved carboxy-terminal tetraticopeptide repeat domain. Recombinant human AIP protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Name Alternative
AH receptor-interacting protein, Aryl-hydrocarbon receptor-interacting protein, HBV X-associated protein 2, XAP-2, Immunophilin homolog ARA9, Aryl hydrocarbon receptor-associated protein 9, FKBP16, FKBP prolyl isomerase 16, FK506-binding protein 37, FKBP37
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
39.8 kDa (350aa) confirmed by MALDI-TOF
Additionnal Information
AIP, Aryl hydrocarbon receptor interacting protein, ARA9, FKBP37, XAP2, ATGP1137-10 µg, ATGP1137-20 µg, ATGP1137-50 µg, ATGP1137-100 µg, ATGP1137-250 µg, ATGP1137-500 µg, ATGP1137-1 mg, ATGP1137-10, ATGP1137-20, ATGP1137-50, ATGP1137-100, ATGP1137-250, ATGP1137-500, ATGP1137-1
References & Citations
Kazlauskas A., et al. (2000) J Biol Chem. 275:41317-41324.; ; Meyer BK., et al. (1998) Mol Cell Biol. 18:978-988.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol
Scientific Category
Signal Transduction
NCBI Accession Number
AAI04828
Uniprot Accession Number
O00170
Species
Human
AA Sequence
MADIIARLRE DGIQKRVIQE GRGELPDFQD GTKATFHYRT LHSDDEGTVL DDSRARGKPM ELIIGKKFKL PVWETIVCTM REGEIAQFLC DIKHVVLYPL VAKSLRNIAV GKDPLEGQRH CCGVAQMREH SSLGHADLDA LQQNPQPLIF HMEMLKVESP GTYQQDPWAM TDEEKAKAVP LIHQEGNRLY REGHVKEAAA KYYDAIACLK NLQMKEQPGS PEWIQLDKQI TPLLLNYCQC KLVVEEYYEV LDHCSSILNK YDDNVKAYFK RGKAHAAVWN AQEAQADFAK VLELDPALAP VVSRELRALE ARIRQKDEED KARFRGIFSH

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