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Recombinant human DTYMK protein

CAT: 0112-ATGP1114-020Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP1114-020Size:20 µg
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Description
DTYMK is also known as thymidylate kinase family and is involved in pyrimidine metabolism. Specifically, DTYMK catalyzes the ATP-dependent conversion of dTMP (deoxythymidine monophosphate) to dTDP (deoxythymidine diphosphate), which then functions as one of the four nucleotides in DNA. Via its role in the catalytic creation of dTDP, DTYMK plays an important role in the pathway of DNA synthesis and is thought to be involved in cell cycle progression and cell growth. Recombinant human DTYMK protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Name Alternative
Thymidylate kinase, CDC8, FLJ44192, MGC198617, PP3731, TMPK, TYMK
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 95% by SDS-PAGE
Molecular Weight
26 kDa (232aa) confirmed by MALDI-TOF
Additionnal Information
DTYMK, Thymidylate kinase, CDC8, FLJ44192, MGC198617, PP3731, TMPK, TYMK, ATGP1114-10 µg, ATGP1114-20 µg, ATGP1114-50 µg, ATGP1114-100 µg, ATGP1114-250 µg, ATGP1114-500 µg, ATGP1114-1 mg, ATGP1114-10, ATGP1114-20, ATGP1114-50, ATGP1114-100, ATGP1114-250, ATGP1114-500, ATGP1114-1
References & Citations
Cummins RR., et al. (1980) Cancer Res. 40 (4) :1235-9.; ; Su JY., et al. (1991) Nucleic Acids Res. 19 (4) :823-7.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 2mM DTT, 0.1M NaCl
Scientific Category
Cell Cycle
NCBI Accession Number
NP_036277.2
Uniprot Accession Number
P23919
Species
Human
AA Sequence
MAARRGALIV LEGVDRAGKS TQSRKLVEAL CAAGHRAELL RFPERSTEIG KLLSSYLQKK SDVEDHSVHL LFSANRWEQV PLIKEKLSQG VTLVVDRYAF SGVAFTGAKE NFSLDWCKQP DVGLPKPDLV LFLQLQLADA AKRGAFGHER YENGAFQERA LRCFHQLMKD TTLNWKMVDA SKSIEAVHED IRVLSEDAIR TATEKPLGEL WK

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